HISTONE DEACETYLASE INHIBITORS IMPROVE THE REPLICATION OF ONCOLYTIC HERPES SIMPLEX VIRUS IN BREAST CANCER CELLS.

Histone deacetylase inhibitors improve the replication of oncolytic herpes simplex virus in breast cancer cells.

New therapies are needed for metastatic breast cancer patients.Oncolytic herpes simplex virus (oHSV) is an exciting therapy being developed for use against aggressive tumors and established metastases.Although oHSV have been demonstrated safe in clinical trials, a lack of sufficient potency has slowed the clinical application of this approach.We ut

read more




Grasping the Discrete Link between Filming and Videoconferencing in the Courtroom. Reflections from the French Case

Filming and transmitting hearings on the one hand, and conducting them by videoconferencing on the other, are generally addressed through different issues and analytical lenses.In this paper we have used the French experience to show that, in fact, the two activities Brogue Shoes have some features in common.We have tried to highlight the real but

read more